Recombinant Human LETM1

• Cat.No.: LETM1-29424TH
• Product Overview: Recombinant fragment corresponding to amino acids 601-708 of Human LETM1 with an N terminal proprietary tag; Predicted MWt 37.51 kDa.

Specification

• Description: This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.
• Protein length: 108 amino acids
• Molecular Weight: 37.510kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANG MPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKD GKVNIDDLVKVIELVDKEDVHISTSQVA
• Sequence Similarities: Contains 1 EF-hand domain.Contains 1 LETM1 domain.
• Tag: Non

Gene Information

• Gene Name: LETM1 leucine zipper-EF-hand containing transmembrane protein 1 [ Homo sapiens ]
• Official Symbol: LETM1
• Synonyms: LETM1; leucine zipper-EF-hand containing transmembrane protein 1; LETM1 and EF-hand domain-containing protein 1, mitochondrial; Mdm38 homolog (yeast)
• Gene ID: 3954
• mRNA Refseq: NM_012318
• Protein Refseq: NP_036450
• MIM: 604407
• Uniprot ID: O95202
• Chromosome Location: 4p16.3
• Function: calcium ion binding; protein binding