Recombinant Human LAP3, His-tagged

• Cat.No.: LAP3-27947TH
• Product Overview: Recombinant fragment, corresponding to amino acids 78-468 of Human LAP3 with an N terminal His tag. Predicted mwt: 43 kDa

Specification

• Description: LAP3 is presumably involved in the processing and regular turnover of intracellular proteins. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Reduced enzymatic activity of LAP3 may cause hypertension.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 45 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: LKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEG KENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGA VLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFA SGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVH IRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPN ANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGA ATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDV VRAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIL NAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIET GDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAA AFL
• Protein length: 78-468 a.a.

Gene Information

• Gene Name: LAP3 leucine aminopeptidase 3 [ Homo sapiens ]
• Official Symbol: LAP3
• Synonyms: LAP3; leucine aminopeptidase 3; PEPS, peptidase S; cytosol aminopeptidase; LAP; LAPEP
• Gene ID: 51056
• mRNA Refseq: NM_015907
• Protein Refseq: NP_056991
• MIM: 170250
• Uniprot ID: P28838
• Chromosome Location: 4p15.33
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: aminopeptidase activity; magnesium ion binding; manganese ion binding; metalloexopeptidase activity; peptidase activity