Recombinant Human KPNA2, T7-tagged

• Cat.No.: KPNA2-2900H
• Product Overview: Recombinant HumanKPNA2 (1-529 aa) is expressed in E.Coli with a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-529 a.a.
• Description: Importins are involved in nuclear import and belong to a seperate class of Ran-GTP binding proteins. Importin α itself does not interact with the nuclear pore complex but functions as an adaptor that binds importin β. It is required to mediate binding of substrates to their receptors. Importin α binds directly to the nuclear localization signal of substrates.
• MW: 57862 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [ Homo sapiens ]
• Synonyms: KPNA2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); QIP2; RCH1; IPOA1; SRP1alpha; KPNA2; karyopherin alpha 2; pendulin; RAG cohort 1; importin alpha 1; importin alpha 2 importin-alpha-P1; Karyopherin subunit alpha-2; RAG cohort protein 1
• Gene ID: 3838
• mRNA Refseq: NM_002266
• Protein Refseq: NP_002257
• MIM: 600685
• UniProt ID: P52292
• Chromosome Location: 17q24.2
• Function: histone deacetylase binding; nuclear localization sequence binding; protein binding; protein transporter activity