Recombinant Human KLRC1&KLRD1 protein, His-tagged

• Cat.No.: KLRC1&KLRD1-715H
• Product Overview: Human NKG2A&CD94 heterodimer Protein is expressed from mammalian with a His &Tag at the N-terminal. It contains CD94(Ser34-Ile179)&NKG2A (Arg100-Leu233).

Specification

• Species: Human
• Source: HEK293
• Tag: His
• ProteinLength: CD94(Ser34-Ile179)&NKG2A (Arg100-Leu233)
• Description: CD94/NKG2 is a family of C-type lectin receptors which are expressed predominantly on the surface of NK cells and a subset of CD8+ T-lymphocyte. These receptors stimulate or inhibit cytotoxic activity of NK cells, therefore they are divided into activating and inhibitory receptors according to their function. CD94/NKG2 recognize nonclassical MHC glycoproteins class I.
• Form: Supplied as 0.22um filtered solution in 20mM PB, 150mM NaCl (pH 7.4).
• Molecular Mass: The protein has a predicted MW of CD94 17.9kDa & NKG2A 17.4kDa.Due to glycosylation, the protein migrates to 33-48KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.5EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: KLRC1&KLRD1
• Official Symbol: KLRC1&KLRD1
• Synonyms: CD159 antigen-like family member A; CD159a antigen; CD159a; NKG2A; NKG2-A; NKG2-A/B type II integral membrane protein; NKG2-A/B-activating NK receptor; CD94 antigen; CD94; CD94natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; NK cell receptor
• Gene ID: 3821 & 3824
• mRNA Refseq: NM_001304448.1 & NM_001114396.3
• Protein Refseq: NP_001291377.1 & NP_001107868.2
• MIM: 161555 & 602894
• UniProt ID: P26715 & Q13241