Recombinant Human KIR2DL3 protein, His-Avi-tagged

• Cat.No.: KIR2DL3-804H
• Product Overview: Recombinant Human KIR2DL3 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains His 22-His 245.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: His 22-His 245
• Description: KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 27.3 KDa. Due to glycosylation, the protein migrates to 45-52KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: KIR2DL3
• Official Symbol: KIR2DL3
• Synonyms: CD158 antigen-like family member B2; CD158b2 antigen; CD158b2; CD158B2CD158b; cl-6; killer cell immunoglobulin-like receptor 2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; Killer inhibitory receptor cl 2-3; KIR-023GB; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; MHC class I NK cell receptor; natural killer associated transcript 2; natural killer cell inhibitory receptor KIR2DL3; Natural killer-associated transcript 2; NKAT; NKAT2; NKAT-2; NKAT2A; nkat2b; NKAT2GL183; NK-receptor; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58; p58.2 MHC class-I specific NK receptor; p58.2 MHC class-I-specific NK receptor
• Gene ID: 3804
• mRNA Refseq: NM_015868.2
• Protein Refseq: NP_056952.2
• MIM: 604938
• UniProt ID: P43628