Recombinant Human JAK2 protein, His-tagged

Description :	This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 34.9kDa; Accurate Molecular Mass: 35kDa as determined by SDS-PAGE reducing conditions.
Protein length :	Asn508~Ala800
Purity :	>92%
Characteristic :	Isoelectric point is 6.7.
Applications :	Cell culture; Activity Assays; In vivo assays.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer :	20mM Tris, 150mM NaCl, pH8.0, containing 0.05% sarcosyl and 5% trehalose.
Reconstitution :	Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Name	JAK2 Janus kinase 2 [ Homo sapiens (human) ]
Official Symbol	JAK2
Synonyms	JAK2; Janus kinase 2; JTK10; THCYT3; tyrosine-protein kinase JAK2; JAK-2; Janus kinase 2 (a protein tyrosine kinase)
Gene ID	3717
mRNA Refseq	NM_001322194.1
Protein Refseq	NP_001309123.1
UniProt ID	O60674