Recombinant Human JAK2 Protein, DYKDDDDK-tagged

• Cat.No.: JAK2-151H
• Product Overview: Recombinant Human Janus kinase 2(JAK2)(NM_004972) protein, with a DYKDDDDK tag, was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: Flag
• Description: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.37, without any preservatives.
• Molecular Mass: 130.5 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: JAK2 Janus kinase 2 [ Homo sapiens ]
• Official Symbol: JAK2
• Synonyms: JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3
• Gene ID: 3717
• mRNA Refseq: NM_004972
• Protein Refseq: NP_004963
• MIM: 147796
• UniProt ID: O60674