Recombinant Human IVNS1ABP Protein (I2-F642), His/Strep tagged

• Cat.No.: IVNS1ABP-0589H
• Product Overview: Recombinant Human 8His-StrepII-TEV-(GG)-IVNS1ABP(I2-F642 end) Protein was expressed in Insect cell.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His&Strep
• Protein Length: I2-F642
• Description: Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: IVNS1ABP influenza virus NS1A binding protein [ Homo sapiens (human) ]
• Official Symbol: IVNS1ABP
• Synonyms: IVNS1ABP; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; HSPC068; KIAA0850; KLHL39; ND1; NS 1; NS1 BP; NS1-binding protein; NCX downstream gene 1; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; NS-1; NS1BP; FLARA3; NS1-BP; FLJ10069; FLJ10411; FLJ10962; FLJ35593; FLJ36593; DKFZp686K06216
• Gene ID: 10625
• mRNA Refseq: NM_006469
• Protein Refseq: NP_006460
• MIM: 609209
• UniProt ID: Q9Y6Y0