Recombinant Human ITGA4(R591L & R878Q)&ITGB7 protein, hFc-tagged

• Cat.No.: ITGA4&ITGB7-1567H
• Product Overview: Recombinant Human ITGA4&ITGB7 protein(P13612.3&P26010.1)(Tyr34-Gln970, R591L & R878Q&Glu20-His723), fused with C-terminal hFc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• ProteinLength: 34-977;20-723 a.a.
• Form: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Bio-activity: Measured by its binding ability in a functional ELISA. Recombinant Human Integrin alpha 4 beta 7/LPAM-1 Fc Chimera binds Recombinant Human MAdCAM-1 Fc Chimera with an ED50 of 30.0-450 ng/mL.
• Molecular Mass: 130 kDa (Integrin alpha 4) & 104 kDa (Integrin beta 7)
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Storage: 12 months from date of receipt, -20 to -70 °C as supplied.
  1 month, 2 to 8 °C under sterile conditions after reconstitution.
  3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.

Gene Information

• Gene Name: ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) [ Homo sapiens ]
• Official Symbol: ITGA4
• Synonyms: ITGA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49D; integrin alpha-4; CD49d; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor, alpha 4 subunit; IA4; MGC90518
• Gene ID: 3676
• mRNA Refseq: NM_000885
• Protein Refseq: NP_000876
• MIM: 192975
• UniProt ID: P13612