Description :	IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Conjugation :	HIS
Form :	Liquid
Purity :	>90% by SDS-PAGE
Storage buffer :	Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, pH 8
Storage :	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids :	MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKHAAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP
Sequence Similarities :	Belongs to the IRF family.Contains 1 IRF tryptophan pentad repeat DNA-binding domain.
Protein length :	1-114 a.a.

Gene Name	IRF1 interferon regulatory factor 1 [ Homo sapiens ]
Official Symbol	IRF1
Synonyms	IRF1; interferon regulatory factor 1; MAR;
Gene ID	3659
mRNA Refseq	NM_002198
Protein Refseq	NP_002189
MIM	147575
Uniprot ID	P10914
Chromosome Location	5q23-q31
Pathway	Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Function	regulatory region DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;