Recombinant Human Interleukin 22
Cat.No. : | IL22-555H |
Product Overview : | IL22 HumanRecombinant produced in E. Coli is a single, non-glycosylated homodimericpolypeptide chain containing 2 x 146 amino acids and having a total MW 33.607kDalton. |
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Species : | Human |
Source : | Human |
Tag : | Non |
Description : | Interleukin-22 (IL22)is protein that in humans is encoded by the IL22 gene. IL22 a member of agroup of cytokines called the IL-10 family or IL-10 superfamily (includingIL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatoryresponses. It shares use of IL-10R2 in cell signaling with other members ofthis family, IL-10, IL-26, IL-28A/B and IL-29. |
Form : | Lyophilized.Each mg contains 1.6 mg mannitol and 1.2 mg HSA. |
Purity : | Greater than 97.0%by SDS-PAGE gel and RF-HPLC. |
Sequence : | The sequence of thefirst five N-terminal amino acids is Met-Ala-Pro-Ile-Ser. |
Molecular Weight : | 33.607kDalton |
Biological Activity : | BiologicalAcitivity was determined by the ability to activiate STAT following receptor ligandinteraction. |
Endotoxin Level : | Less than0.1 ng per µg (1 EU/µg) of protein. |
Reconstitution : | Centrifugevial prior to opening. First add sterile water to the vial to fullysolubilize the protein to a concentration not less than 100 µg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. |
Storage : | Lyophilizedsamples are stable at room temperature for 3 weeks, but it is recommended tostore them desiccated at -20°C to -80°C. Upon reconstitution, protein shouldbe stored at 2-4°C for one week and for six months at -20°C to -80°C. Add acarrier protein (0.1% HSA or BSA) as a stabilizer for long term storage.Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | IL22 |
Gene Name | IL22interleukin 22 [ Homo sapiens ] |
Synonyms | IL22; interleukin 22; TIFa; IL21; IL-21; IL-22; ILTIF; IL-TIF;IL-D110; zcyto18;ZCYTO183; MGC79382; MGC79384; TIFIL-23; interleukin 21;interleukin-22;cytokine Zcyto18; OTTHUMP00000240117; IL-10-related T-cell-derived induciblefactor; IL-10-related T-cell-derived-inducible factor |
Gene ID | 50616 |
mRNA Refseq | NM_020525 |
Protein Refseq | NP_065386 |
MIM | 605330 |
UniProt ID | Q9GZX6 |
Chromosome Location | 12q15 |
Pathway | Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway |
Function | cytokineactivity; interleukin-22 receptor binding |
◆ Recombinant Proteins | ||
IL22-15M | Active Recombinant Mouse IL22 Protein, His-Tagged | +Inquiry |
Il22-1673R | Recombinant Rat Il22 Protein, His-tagged | +Inquiry |
IL22-4375C | Recombinant Cynomolgus Monkey IL22 Protein | +Inquiry |
IL22-91H | Recombinant Human IL22 Protein, His-tagged | +Inquiry |
Il22-28M | Recombinant Mouse Interleukin-22 | +Inquiry |
◆ Cell & Tissue Lysates | ||
IL22-5232HCL | Recombinant Human IL22 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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