Recombinant Human Interleukin 17D

• Cat.No.: IL17D-167H
• Product Overview: Recombinant Human IL-17D produced inE.coliis a disulfide-linked homodimer with a total weight of 40.5 kDa, consisting of 370 amino acid residues.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays.
• Purity: > 98% by SDS-PAGE and HPLC analysis.
• Endotoxin Level: < 0.1 ng per ug of IL-17D.
• Stabilizer: None.
• Formulation: Lyophilized.
• Biological Activity: Testing in progress.
• Reconstitution: The human IL-17D should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃.
• Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17D should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL17D interleukin 17D [ Homo sapiens ]
• Synonyms: IL17D; interleukin 17D;IL27; IL-22; IL-27; IL-17D; FLJ30846; interleukin 27; Interleukin-17D; Interleukin-27; OTTHUMP00000018104
• Gene ID: 53342
• mRNA Refseq: NM_138284
• Protein Refseq: NP_612141
• MIM: 607587
• UniProt ID: Q8TAD2
• Chromosome Location: 13q11
• Function: cytokine activity