Recombinant Human Interleukin 17C, His-tagged

• Cat.No.: IL17C-291H
• Product Overview: Recombinant human IL-17C with His-tag was expressed inInsect cell.MW= 19.793 kDa.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1β from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Human IL-17C cDNA encodes a 197 amino acid protein with a putative 18 amino acid signal peptide. The recombinant human IL-17C is a disulfide-linked homodimer composed of a 19.8 kDa monomeric subunit.
• Handling Conditions: For best recovery, quick-spin vial prior to opening. Use in a sterile environment.
• Purity: Greater than 98% as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.01 ng/ug cytokine as determined by the LAL assay.
• Bioactivity: Testing in progress.
• Formulation: 20 mM Phosphate, 0.2 M NaCl, pH 6.0, with 1.0% BSA.
• Temperature Limitation: Store at less than or equal to –70°C.

Gene Information

• Gene Name: IL17C interleukin 17C [ Homo sapiens ]
• Synonyms: interleukin 17C; CX2; IL-21; IL-17C; MGC126884; MGC138401; IL17C; interleukin-17C; cytokine CX2; Cytokine CX2
• Gene ID: 27189
• mRNA Refseq: NM_013278
• Protein Refseq: NP_037410
• UniProt ID: Q9P0M4
• Chromosome Location: 16q24
• MIM: 604628
• Function: cytokine activity