Recombinant Human Interleukin 13, His-tagged

• Cat.No.: IL13-44H
• Product Overview: Recombinant Human Interleukin-13 His produced inE.Coliis a single, non-glycosylated, Polypeptide chain containing 112 amino acids fragment (21-132) having a molecular weight of 12.84 kDa with a 4 kDa amino-terminal his-tagged. The IL-13 His is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 21-132 a.a.
• Description: Interleukin-13 is a pleiotropic regulatory cytokine, which shares many of the properties of Interleukin-4. IL-13 is produced primarily by activated T lymphocytes and acts via specific cell surface receptor complexes. Its biological activities include the stimulation of B-cell proliferation and differentiation and the regulation of inflammatory and immune responses.
• Physical Appearance: Sterile Filtered clear solution (0.1 mg/ml).
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Formulation: Interleukin -13 His-Tag protein is supplied in 50mM Sodium Acetate (pH 4.8) and 50% glycerol.
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: IL13 interleukin 13 [ Homo sapiens ]
• Synonyms: IL13; interleukin 13; ALRH; BHR1; P600; IL-13; MGC116786; MGC116788; MGC116789; Interleukin-13; NC30
• Gene ID: 3596
• mRNA Refseq: NM_002188
• Protein Refseq: NP_002179
• MIM: 147683
• UniProt ID: P35225
• Chromosome Location: 5q31
• Pathway: Asthma; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Jak-STAT signaling pathway
• Function: cytokine activity; interleukin-13 receptor binding; protein binding