Recombinant Human INA

• Cat.No.: INA-64H
• Product Overview: Recombinant Human Alpha-internexin produced inE.coliis a 66kDa, type IV intermediate filament protein that is expressed in neurons during development of the peripheral and central nervous systems, as well as in a few neurons of the adult central nervous system.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Alpha-internexin, is a Class IV intermediate filament approximately 66 KDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the Central Nervous System of adults. The protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.
• Presentation: 100µl purified human α-Internexin protein at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% glycerol.
• Application and Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant PTEN shows a band at 45 kDa antibody reactive.
• Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: INA internexin neuronal intermediate filament protein, alpha [ Homo sapiens ]
• Synonyms: NEF5; NF-66; TXBP-1; FLJ18662; FLJ57501; MGC12702; INA;internexin neuronal intermediate filament protein, alpha; neurofilament 5 (66kD); neurofilament-66, tax-binding protein; Alpha-internexin; Alpha-Inx; 66 kDa neurofilament protein; Neurofilament-66
• Gene ID: 9118
• mRNA Refseq: NM_032727
• Protein Refseq: NP_116116
• MIM: 605338
• UniProt ID: Q16352
• Chromosome Location: 10q24
• Function: structural constituent of cytoskeleton