Recombinant Human IL20 protein, His-tagged

• Cat.No.: IL20-588H
• Product Overview: Recombinant Human IL20 (Q9NYY1) aa. (Leu25~Glu176) fused with His tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.2kDa; Accurate Molecular Mass: 21kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Leu25~Glu176
• Purity: >92%
• Characteristic: Isoelectric point is 8.9.
• Applications: Cell culture; Activity Assays; In vivo assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 0.05% sarcosyl and 5% trehalose.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: IL20 interleukin 20 [ Homo sapiens (human) ]
• Official Symbol: IL20
• Synonyms: IL20; interleukin 20; IL-20; IL10D; ZCYTO10; interleukin-20; cytokine Zcyto10; four alpha helix cytokine
• Gene ID: 50604
• mRNA Refseq: NM_018724.3
• Protein Refseq: NP_061194.2
• UniProt ID: Q9NYY1