Recombinant Human IL1RN Protein, MYC/DDK-tagged

Cat.No. : IL1RN-1819H
Product Overview : Recombinant human IL1RN protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
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Description : The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]
Source : HEK293
Species : Human
Tag : Myc&DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 16 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name IL1RN interleukin 1 receptor antagonist [ Homo sapiens ]
Official Symbol IL1RN
Synonyms DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Gene ID 3557
mRNA Refseq NM_000577
Protein Refseq NP_000568
MIM 147679
UniProt ID P18510

Not For Human Consumption!

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