Recombinant Human IL1R2 Protein, MYC/DDK-tagged
Cat.No. : | IL1R2-1821H |
Product Overview : | Recombinant human IL1R2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
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Description : | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 43.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | IL1R2 interleukin 1 receptor, type II [ Homo sapiens ] |
Official Symbol | IL1R2 |
Synonyms | CD121b; IL1RB; MGC47725 |
Gene ID | 7850 |
mRNA Refseq | NM_004633 |
Protein Refseq | NP_004624 |
MIM | 147811 |
UniProt ID | P27930 |
Not For Human Consumption!
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