Recombinant Human IL12B Protein

• Cat.No.: IL12B-77H
• Product Overview: Recombinant Human Interleukin-12 subunit beta is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328 is expressed.

Specification

• Species: Human
• Source: Human Cells
• Protein Length: 23-328 a.a.
• Description: Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
• Form: Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
• AA Sequence: Ile23-Ser328
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug).
• Shipping: Ambient

Gene Information

• Gene Name: IL12B interleukin 12B [ Homo sapiens (human) ]
• Official Symbol: IL12B
• Synonyms: Interleukin-12 subunit beta; Cytotoxic lymphocyte maturation factor 40 kDa subunit; p40, IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
• Gene ID: 3593
• mRNA Refseq: NM_002187.3
• Protein Refseq: NP_002178.2
• MIM: 161561
• UniProt ID: P29460