Recombinant Human IGFBP2 Protein, His-tagged

• Cat.No.: IGFBP2-991H
• Product Overview: Recombinant Human IGFBP2 Protein (Asp148-Gln325) with His tag was expressed in 293F.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Asp148-Gln325
• Description: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.6 kDa; Accurate Molecular Mass: 21 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: IGFBP2 insulin-like growth factor binding protein 2, 36kDa [ Homo sapiens (human) ]
• Official Symbol: IGFBP2
• Synonyms: IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2, insulin like growth factor binding protein 2 (36kD); insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; IBP2; IGF-BP53
• Gene ID: 3485
• mRNA Refseq: NM_000597
• Protein Refseq: NP_000588
• MIM: 146731
• UniProt ID: P18065