Recombinant Human IFNAR1 protein, His-tagged

• Cat.No.: IFNAR1-6938H
• Product Overview: Recombinant Human IFNAR1 aa. (Leu25~Ser146) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 18kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Leu25~Ser146
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.3.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH 7.4, containing 5% sucrose.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: IFNAR1 interferon alpha and beta receptor subunit 1 [ Homo sapiens (human) ]
• Official Symbol: IFNAR1
• Synonyms: IFNAR1; interferon alpha and beta receptor subunit 1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; interferon alpha/beta receptor 1; CRF2-1; IFN-R-1; IFN-alpha/beta receptor 1; alpha-type antiviral protein; beta-type antiviral protein; cytokine receptor class-II member 1; cytokine receptor family 2 member 1; interferon (alpha, beta and omega) receptor 1; interferon receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
• Gene ID: 3454
• mRNA Refseq: NM_000629.2
• Protein Refseq: NP_000620.2
• UniProt ID: P17181