Recombinant Human ICAM3, His-tagged

• Cat.No.: ICAM3-14032H
• Product Overview: Recombinant Human ICAM3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 200-547a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ICAM3 intercellular adhesion molecule 3 [ Homo sapiens ]
• Official Symbol: ICAM3
• Synonyms: ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM R; ICAM-3; intercellular adhesion molecule-3; ICAM-R
• Gene ID: 3385
• mRNA Refseq: NM_002162
• Protein Refseq: NP_002153
• MIM: 146631
• UniProt ID: P32942
• Chromosome Location: 19p13.3-p13.2
• Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem
• Function: integrin binding; protein binding; receptor binding