Recombinant Human ICAM2 protein, His-tagged

• Cat.No.: ICAM2-3163H
• Product Overview: Recombinant Human ICAM2 (Ser22-Gln223) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2/CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
• Source: HEK293
• Species: Human
• Tag: His
• Predicted N Terminal: Ser22
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 23.3 kDa. The protein migrates as 40-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: Ser22-Gln223
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: ICAM2
• Official Symbol: ICAM2
• Synonyms: ICAM2; intercellular adhesion molecule 2; CD102; ICAM-2
• Gene ID: 3384
• mRNA Refseq: NM_000873
• Protein Refseq: NP_000864
• MIM: 146630
• UniProt ID: P13598