Recombinant Human HSPA13, His-tagged

• Cat.No.: HSPA13-3408H
• Product Overview: Recombinant human HSPA13 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: HSPA13, also known as STCH, is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. HSPA13 has been found to interact with PLIC-1 and PLIC-2, proteins involved in the signaling connection between the membrane receptors for thrombospondin and the cytoskeleton.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol.
• Molecular Weight: 54.3 kDa (489aa) confirmed by MALDI-TOF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM QQYLPLPTPK VIG IDLGTTY CSVGVFFPGT GKVKVIPDEN GHISIPSMVS FTDNDVYVGY ESV EL ADSNP QNTIYDAKRF IGKIFTAEEL EAEIGRYPFK VLNKNGMVEF SVTSNETITV SPEYVGSRLL LKLKEMAEAY LGMPVANAVI SVPAEFDLKQ RNSTIEAANL AGL KIL RVIN EPTAAAMAYG LHKADVFHVL VIDLGGGTLD VSLLNKQGGM FLTRAMSGNN KL GGQDFNQR LLQYLYKQIY QTYGFVPSRK EEIHRLRQAV EMVKLNLTLH QS AQ LSVLLT VEEQDRKEPH SSDTELPKDK LSSADDHRVN SGFGRGLSDK KS GE SQ VL FE TEISRKLFDT LNEDLFQKIL VPIQQVLKEG HLEKTEIDEV VLVGGSTRIP RIR Q V IQEFF GKDPNTSVDP DLAVVTGVAI QAGIDGGFWP LQVSALEIPN KHL QK TN F N.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HSPA13 heat shock protein 70kDa family, member 13 [ Homo sapiens ]
• Synonyms: heat shock protein 70kDa family, member 13; STCH; HSPA13; heat shock 70 kDa protein 13; microsomal stress 70 protein ATPase core; microsomal stress-70 protein ATPase core; stress 70 protein chaperone, microsome-associated, 60kD; stress 70 protein chaperone, microsome-associa-ted, 60kDa; stress-70 protein chaper-one microsome-associated 60 kDa protein;Microsomal stress-70 protein ATPase core; Stress-70 protein chape-ronnnne microsome-associated 60 kDa protein
• Gene ID: 6782
• mRNA Refseq: NM_006948
• Protein Refseq: NP_008879
• MIM: 601100
• UniProt ID: P48723
• Chromosome Location: 21q11.1; 21q11
• Function: ATP binding; nucleotide binding