Recombinant Human HSF2, His-tagged

• Cat.No.: HSF2-7713H
• Product Overview: Recombinant Human Heat Shock Factor Protein 2/HSF2 is produced by our E. coli expression system. The target protein is expressed with sequence (Ser411Ser536) of Human HSF2 fused with a 6His tag at the Nterminus.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heatshock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. HSF2 is widely expressed in many cells and tissues. HSF2 is located on Cytoplasmic during normal growth. But when it is activited, HSF2 moves to the nucleus.
• Form: Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MSENKGLETT KNNVVQPVSE EGRKSKSKPD KQLIQYTAFP LLAFLDGNP ASSVEQASTT ASSEVLSSVD KPIEVDELLD SSLDPEPTQS KLVRLEPLTE A EASEATLF YLCELAPAPL DSDMPLLDS*
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.

Gene Information

• Gene Name: HSF2 heat shock transcription factor 2 [ Homo sapiens ]
• Official Symbol: HSF2
• Synonyms: HSF2; heat shock transcription factor 2; heat shock factor protein 2; HSF 2; HSTF 2; MGC75048; MGC117376; MGC156196
• Gene ID: 3298
• mRNA Refseq: NM_001135564
• Protein Refseq: NP_001129036
• MIM: 140581
• UniProt ID: Q03933
• Chromosome Location: 6q22
• Function: protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity