Recombinant Human HSD17B11, His-tagged

• Cat.No.: HSD17B11-13955H
• Product Overview: Recombinant Human HSD17B11 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 15-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 [ Homo sapiens ]
• Official Symbol: HSD17B11
• Synonyms: HSD17B11; hydroxysteroid (17-beta) dehydrogenase 11; dehydrogenase/reductase (SDR family) member 8 , DHRS8; estradiol 17-beta-dehydrogenase 11; 17 BETA HSD11; 17 BETA HSDXI; PAN1B; retinal short chain dehydrogenase/reductase 2; RetSDR2; SDR16C2; short chain dehydrogenase/reductase family 16C; member 2; 17-BETA-HSD11; 17-BETA-HSDXI; 17-beta-HSD 11; 17-beta-HSD XI; CTCL tumor antigen HD-CL-03; CTCL-associated antigen HD-CL-03; 17-beta-hydroxysteroid dehydrogenase 11; 17-beta-hydroxysteroid dehydrogenase XI; T-cell lymphoma-associated antigen HD-CL-03; dehydrogenase/reductase SDR family member 8; 17-beta-hydroxysteroid dehydrogenase type XI; dehydrogenase/reductase (SDR family) member 8; retinal short-chain dehydrogenase/reductase 2; cutaneous T-cell lymphoma-associated antigen HD-CL-03; short chain dehydrogenase/reductase family 16C, member 2; DHRS8; RETSDR2; 17BHSD11
• Gene ID: 51170
• mRNA Refseq: NM_016245
• Protein Refseq: NP_057329
• MIM: 612831
• UniProt ID: Q8NBQ5
• Chromosome Location: 4q22.1
• Function: estradiol 17-beta-dehydrogenase activity; nucleotide binding; steroid dehydrogenase activity