Recombinant Human HscB Iron-Sulfur Cluster Co-Chaperone Homolog (E. coli), His-tagged

• Cat.No.: HSCB-6850H
• Product Overview: Recombinant human HSCB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: HSCB belongs to the hscB family and contains 1 J domain. This protein is expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart and localized to mitochondria and cytoplasm. It may act as a co-chaperone in iron-sulfur cluster assembly in mitochondria, Interacts with ISCU and HSPA9.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl.
• Molecular Mass: 26.7kDa(231aa) confirmed by MALDI-TOF
• Protein length: 30-235aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAASQA GSNYPRCWNC GGPWGPGRED RFFCPQCRAL QAPDPTRDYF SLMDCNRSFR VDTAKLQHRY QQLQRLVHPD FFSQRSQTEK DFSEKHSTLV NDAYKTLLAP LSRGLYLLKL HGIEIPERTD YEMDRQFLIE IMEINEKLAE AESEAAMKEI ESIVKAKQKE FTDNVSSAFE QDDFEEAKEI LTKMRYFSNI EEKIKLKKIP L
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HSCB HscB iron-sulfur cluster co-chaperone homolog (E. coli) [ Homo sapiens ]
• Official Symbol: HSCB
• Synonyms: HSCB; HscB iron-sulfur cluster co-chaperone homolog (E. coli); JAC1; HSC20; DNAJC20; dJ366L4.2; iron-sulfur cluster co-chaperone protein HscB, mitochondrial; J-type co-chaperone HSC20; dnaJ homolog subfamily C member 20; DnaJ (Hsp40) homolog, subfamily C, member 20; Jac1
• Gene ID: 150274
• mRNA Refseq: NM_172002
• Protein Refseq: NP_741999
• MIM: 608142
• UniProt ID: Q8IWL3
• Chromosome Location: 22q12.1
• Pathway: Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem
• Function: chaperone binding; heat shock protein binding; metal ion binding; molecular_function; protein binding