Recombinant Human HRAS (G12V) Protein, GST-tagged

• Cat.No.: HRAS-702H
• Product Overview: Recombinant Human HRAS protein (NP_005334，G12V) was expressed in E. coli with GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase. The GST-Tag facilitates the protein’s application in typical GST pull-down assays.
• Form: 25 mM Tris-HCl pH 7.5, 150 mM NaCl, 5 mM MgCl2 and 5 mM beta-mercaptoethanol
• Purity: > 95 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog [ Homo sapiens ]
• Official Symbol: HRAS
• Synonyms: CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1
• Gene ID: 3265
• mRNA Refseq: NM_005343.2
• Protein Refseq: NP_005334.1
• MIM: 190020
• UniProt ID: P01112