Recombinant Human HOXA5 Protein, His-tagged

• Cat.No.: HOXA5-01H
• Product Overview: Recombinant human HOXA5 protein with a His-tag was expressed in E. coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
• Molecular Mass: The protein has a calculated MW of 30 kDa.
• AA Sequence: HHHHHHMSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
• Purity: >85% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1 mg/mL
• Storage Buffer: 50mM Tris pH8.0, 300mM NaCl

Gene Information

• Gene Name: HOXA5 homeobox A5 [ Homo sapiens (human) ]
• Official Symbol: HOXA5
• Synonyms: HOXA5; homeobox A5; homeo box A5 , HOX1, HOX1C; homeobox protein Hox-A5; homeo box 1C; homeo box A5; homeobox protein HOXA5; homeobox protein Hox-1C; HOX1; HOX1C; HOX1.3; MGC9376
• Gene ID: 3202
• mRNA Refseq: NM_019102
• Protein Refseq: NP_061975
• MIM: 142952
• UniProt ID: P20719