Recombinant Human HNRNPA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HNRNPA1-3033H
• Product Overview: HNRNPA1 MS Standard C13 and N15-labeled recombinant protein (NP_112420) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 38.6 kDa
• AA Sequence: MSKSESPKEPEQLRKLFIGGLSFET TDESLRSHFEQWGTLTDCVVMRDPN TKRSRGFGFVTYATVEEVDAAMNAR PHKVDGRVVEPKRAVSREDSQRPGA HLTVKKIFVGGIKEDTEEHHLRDYF EQYGKIEVIEIMTDRGSGKKRGFAF VTFDDHDSVDKIVIQKYHTVNGHNC EVRKALSKQEMASASSSQRGRSGSG NFGGGRGGGFGGNDNFGRGGNFSGR GGFGGSRGGGGYGGSGDGYNGFGND GGYGGGGPGYSGGSRGYGSGGQGYG NQGSGYGGSGSYDSYNNGGGGGFGG GSGSNFGGGGSYNDFGNYNNQSSNF GPMKGGNFGGRSSGPYGGGGQYFAK PRNQGGYGGFSSSSSYGSGRRFTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 [ Homo sapiens (human) ]
• Official Symbol: HNRNPA1
• Synonyms: HNRNPA1; heterogeneous nuclear ribonucleoprotein A1; HNRPA1; hnRNP A1; hnRNPA1; hnRNP A1-like 3; hnRNP core protein A1; helix-destabilizing protein; hnRNP core protein A1-like 3; single-strand RNA-binding protein; single-strand DNA-binding protein UP1; nuclear ribonucleoprotein particle A1 protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein core protein A1; Putative heterogeneous nuclear ribonucleoprotein A1-like 3; HNRPA1L3; hnRNP-A1; MGC102835
• Gene ID: 3178
• mRNA Refseq: NM_031157
• Protein Refseq: NP_112420
• MIM: 164017
• UniProt ID: P09651