Recombinant Human Histone Deacetylase 9, His-tagged

• Cat.No.: HDAC9-1596H
• Product Overview: Recombinant human HDAC9 (548-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: HDAC9-1596H
• Description: HDAC9 or MIRT belongs to the histone deacetylase /acuc/apha family and is a component of the histone deacetylase complex. HDAC9 gene is orthologous to the Xenopus and mouse MITR genes (MEF2-interacting transcription repressor). HDAC9 represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 is a calcium-sensitive transcriptional repressor of MEF2.
• Applications: HDAC Assay; Western Blot
• Molecular Weight: 77 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >80%
• Concentration: 0.1 ug/ul
• Specific Activity: 235 RLU/min/ng
• Sequences: 548-end
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: MicroRNAs in cardiomyocyte hypertrophy; Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class II
• Protein length: 548-end a.a.

Gene Information

• Gene Name: HDAC9 histone deacetylase 9 [ Homo sapiens ]
• Official Symbol: HDAC9
• Synonyms: HDAC9; histone deacetylase 9; HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL; KIAA0744; DKFZp779K1053; histone deacetylase 9; OTTHUMP00000201766; OTTHUMP00000201767; OTTHUMP00000201768; OTTHUMP00000201895; OTTHUMP00000201926; OTTHUMP00000201927; OTTHUMP00000225210; OTTHUMP00000225211; OTTHUMP00000225262; OTTHUMP00000231731; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein
• Gene ID: 9734
• mRNA Refseq: NM_178423
• Protein Refseq: NP_848510
• MIM: 606543
• UniProt ID: Q9UKV0
• Chromosome Location: 7p21
• Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; histone deacetylase binding; protein binding; protein deacetylase activity; protein kinase C binding; repressing transcription factor binding; NOT histone deacetylase activity; protein kinase C binding; transcription corepressor activity; histone deacetylase activity