Recombinant Human HIST1H2BL Protein, MYC/DDK-tagged

• Cat.No.: HIST1H2BL-431H
• Product Overview: Recombinant Human HIST1H2BL fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 13.8 kDa
• Identity: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: HIST1H2BL histone cluster 1 H2B family member l [ Homo sapiens ]
• Official Symbol: HIST1H2BL
• Synonyms: H2B/c; H2BFC; dJ97D16.4
• Gene ID: 8340
• mRNA Refseq: NM_003519
• Protein Refseq: NP_003510
• MIM: 602800
• UniProt ID: Q99880