Recombinant Human HIBCH, His-tagged

• Cat.No.: HIBCH-13772H
• Product Overview: Recombinant Human HIBCH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-386a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HIBCH 3-hydroxyisobutyryl-CoA hydrolase [ Homo sapiens ]
• Official Symbol: HIBCH
• Synonyms: HIBCH; 3-hydroxyisobutyryl-CoA hydrolase; 3 hydroxyisobutyryl Coenzyme A hydrolase; 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; HIBYL-CoA-H; HIB-CoA hydrolase; 3-hydroxyisobutyryl-Coenzyme A hydrolase; HIBYLCOAH
• Gene ID: 26275
• mRNA Refseq: NM_014362
• Protein Refseq: NP_055177
• MIM: 610690
• UniProt ID: Q6NVY1
• Chromosome Location: 2q32.3
• Pathway: Branched-chain amino acid catabolism, organism-specific biosystem; Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA, organism-specific biosystem; Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: 3-hydroxyisobutyryl-CoA hydrolase activity; hydrolase activity