Recombinant Human Heat Shock 22kDa Protein 8
Cat.No. : | HSPB8-1254H |
Product Overview : | Recombinant Human Heat Shock Protein 22 was expressed inE.Coli. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | HSP22 displays temperature-dependent chaperone activity. HSP-22 acts as a mn(2+)-dependent serine-threonine- specific protein kinase. we are not convinced that this is its true role. Defects in HSPB8 are a cause of distal hereditary motor neuropathy type ii (DHMN2) also known as distal spinal muscular atrophy (DSMA) and spinal muscular atrophy of the charcot-marie-tooth type. it is an autosomal dominant disorder of lower motor neurons characterized by distal muscle weakness. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Formulation : | The HSP22 protein was lyophilized from a concentrated (1mg/ml) solution containing 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 15mMβ-ME. |
Solubility : | It is recommended to reconstitute the lyophilized HSP22 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Stability : | Lyophilized HSP22 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSP22 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Immunological Activity : | Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSP22. |
Gene Name | HSPB8 heat shock 22kDa protein 8 [ Homo sapiens ] |
Synonyms | heat shock 22kDa protein 8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; HSPB8; E2-induced gene 1; protein kinase H11; heat shock protein beta-8; heat shock 27kDa protein 8; small stress protein-like protein HSP22; HspB8; CRYAC; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22 |
Gene ID | 26353 |
mRNA Refseq | NM_014365 |
Protein Refseq | NP_055180 |
MIM | 608014 |
UniProt ID | Q9UJY1 |
Chromosome Location | 12q24.23 |
Function | protein serine/threonine kinase activity; identical protein binding |
◆ Recombinant Proteins | ||
HSPB8-2025H | Recombinant Human Heat Shock 22kDa Protein 8, His-tagged | +Inquiry |
Hspb8-3457M | Recombinant Mouse Hspb8 Protein, Myc/DDK-tagged | +Inquiry |
HSPB8-1991R | Recombinant Rhesus Macaque HSPB8 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSPB8-165H | Recombinant Human HSPB8 protein, His/MBP-tagged | +Inquiry |
HSPB8-1123H | Recombinant Human HSPB8 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
HSPB8-5345HCL | Recombinant Human HSPB8 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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