Recombinant Human HCFC1 Protein, His-tagged

• Cat.No.: HCFC1-407H
• Product Overview: Recombinant Human HCFC1(Asn52~His258) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Asn52~His258
• Description: This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 26.7kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: HCFC1 host cell factor C1 (VP16-accessory protein) [ Homo sapiens ]
• Official Symbol: HCFC1
• Synonyms: HCFC1; host cell factor C1 (VP16-accessory protein); HFC1; host cell factor 1; CFF; HCF 1; HCF1; MGC70925; VCAF; HCF; C1 factor; VP16 accessory protein; HCF-1
• Gene ID: 3054
• mRNA Refseq: NM_005334
• Protein Refseq: NP_005325
• MIM: 300019
• UniProt ID: P51610