Recombinant Human HAVCR2 Protein, hIgG-His-Tagged

• Cat.No.: HAVCR2-02H
• Product Overview: Recombinant Human HAVCR2 Protein, hIgG-His-Tagged was expressed in Baculovirus cell line.

Specification

• Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
• Source: Baculovirus
• Species: Human
• Tag: His&Fc
• Form: Liquid
• Molecular Mass: 47.3 kDa
• Protein length: 423aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 85% by SDS-PAGE
• Applications: SDS-PAGE
• Notes: Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by absorbance at 280nm)
• Storage Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
  Purity> 85% by SDS-PAGE

Gene Information

• Gene Name: HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens (human) ]
• Official Symbol: HAVCR2
• Synonyms: Hepatitis A virus cellular receptor 2, HAVCR2, HAVcr-2, KIM-3, Tim-3, TIM3, TIMD-3, TIMD3, FLJ14428, HAVcr-2, Havcr2, HAVR2_HUMAN, Hepatitis A virus cellular receptor 2, Kidney injury molecule 3, KIM 3, KIM3, T cell immunoglobulin and mucin domain containing 3, T cell immunoglobulin mucin 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim 3, TIM-3, TIM3, TIMD-3, TIMD3
• Gene ID: 84868
• mRNA Refseq: NM_032782.5
• Protein Refseq: NP_116171.3
• MIM: 606652
• UniProt ID: Q8TDQ0