Recombinant Human H6PD, His-tagged

• Cat.No.: H6PD-13652H
• Product Overview: Recombinant Human H6PD protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 443-791a.a.
• Description: There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) [ Homo sapiens ]
• Official Symbol: H6PD
• Synonyms: H6PD; hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); GDH, glucose dehyrogenase; GDH/6PGL endoplasmic bifunctional protein; G6PD, H form; glucose dehyrogenase; glucose dehydrogenase; glucose 1- dehydrogenase; 6-phosphogluconolactonase; glucose-6-phosphate dehydrogenase, salivary; GDH; G6PDH; MGC87643; DKFZp686A01246
• Gene ID: 9563
• mRNA Refseq: NM_004285
• Protein Refseq: NP_004276
• MIM: 138090
• UniProt ID: O95479
• Chromosome Location: 1p36
• Pathway: Metabolic pathways, organism-specific biosystem; Pentose phosphate pathway, organism-specific biosystem; Pentose phosphate pathway, conserved biosystem; Pentose phosphate pathway (Pentose phosphate cycle), organism-specific biosystem; Pentose phosphate pathway (Pentose phosphate cycle), conserved biosystem; Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P, organism-specific biosystem
• Function: 6-phosphogluconolactonase activity; NADP binding; glucose 1-dehydrogenase [NAD(P)] activity; glucose-6-phosphate dehydrogenase activity; hydrolase activity; oxidoreductase activity; sugar binding