Recombinant Human H3.3 Core Histone Protein

• Cat.No.: H3.3C-315H
• Product Overview: Full length Recombinant Human H3.3 Core Histone Protein containing 2 units of each full length recombinant histone H3.3, H4, H2A and H2B, was produced in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids
  arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin.
  Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric
  nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin
  structure to facilitate transcriptional activation or repression or other nuclear processes. The histone variant H3.3 replaces
  conventional H3.1 in a wide range of nucleosomes in active genes. H3.3 constitutes the predominant form of histone H3 in nondividing
  cells.
• Form: 20 mM Tris-Cl pH 7.9, 2 M NaCl, 1mM EDTA, 0.5 mM PMSF and 1 mM DTT.
• Purity: Purified using FPLC, >98% purity as determined by SDS-PAGE.
• Notes: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
• Stability: Guaranteed stable for 2 years from date of receipt when stored properly.
• Storage: Store at -80 centigrade.
• Concentration: 1 µg/µl
• Full Length: Full L.