Recombinant Human H2AFJ, GST-tagged

• Cat.No.: H2AFJ-13644H
• Product Overview: Recombinant Human H2AFJ protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-129a.a.
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: H2AFJ H2A histone family, member J [ Homo sapiens ]
• Official Symbol: H2AFJ
• Synonyms: H2A histone family, member J; 14456; Ensembl:ENSG00000246705; MGC921, FLJ10903, FLJ52230; histone H2A.J;H2a/j; H2AJ
• Gene ID: 55766
• mRNA Refseq: NM_177925.2
• Protein Refseq: NP_808760.1
• UniProt ID: Q9BTM1
• Chromosome Location: 12p12.3
• Pathway: Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Systemic lupus erythematosus, organism-specific biosystem; Systemic lupus erythematosus, conserved biosystem
• Function: DNA binding; protein heterodimerization activity