Recombinant Human GUCY1B3, His-tagged
Cat.No. : | GUCY1B3-13619H |
Product Overview : | Recombinant Human GUCY1B3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Availability | March 14, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 282-619a.a. |
Description : | Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]). |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name | GUCY1B3 guanylate cyclase 1, soluble, beta 3 [ Homo sapiens ] |
Official Symbol | GUCY1B3 |
Synonyms | GUCY1B3; guanylate cyclase 1, soluble, beta 3; GUC1B3; guanylate cyclase soluble subunit beta-1; GC S beta 1; GC SB3; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3; GUCB3; GC-SB3; GUCSB3; GUCY1B1; GC-S-beta-1; |
Gene ID | 2983 |
mRNA Refseq | NM_000857 |
Protein Refseq | NP_000848 |
MIM | 139397 |
UniProt ID | Q02153 |
Chromosome Location | 4q31.3-q33 |
Pathway | Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Hemostasis, organism-specific biosystem; Long-term depression, organism-specific biosystem; Long-term depression, conserved biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem; |
Function | GTP binding; Hsp90 protein binding; guanylate cyclase activity; heme binding; ion binding; metal ion binding; nucleotide binding; protein heterodimerization activity; receptor activity; |
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Not For Human Consumption!
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