Recombinant Human GTF2H5 protein, His-tagged

• Cat.No.: GTF2H5-55H
• Product Overview: Recombinant Human GTF2H5, fused with N-His tag, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 86aa(including fusion tag)
• Description: This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated inregulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 10kDa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80°C and avoid repeated freeze-thaw cycles

Gene Information

• Gene Name: GTF2H5 general transcription factor IIH subunit 5 [ Homo sapiens ]
• Official Symbol: GTF2H5
• Synonyms: TTD; TFB5; TTD3; TTDA; TFIIH; TTD-A; TGF2H5; C6orf175; bA120J8.2
• Gene ID: 404672
• mRNA Refseq: NM_207118
• Protein Refseq: NP_997001
• MIM: 608780
• UniProt ID: Q6ZYL4
• Chromosome Location: Basal transcription factors, organism-specific biosystem; Disease, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem
• Pathway: rDNA binding