Recombinant Human GSTA1 protein, His-tagged

• Cat.No.: GSTA1-2654H
• Product Overview: Recombinant Human GSTA1 aa. (Ala2~Phe222 (Accession # P08263)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.7kDa
• Protein length: Ala2~Phe222
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.9.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: GSTA1 glutathione S-transferase alpha 1 [ Homo sapiens (human) ]
• Official Symbol: GSTA1
• Synonyms: GSTA1; glutathione S-transferase alpha 1; GST2; GTH1; GSTA1-1; GST-epsilon; glutathione S-transferase A1; GST HA subunit 1; GST class-alpha member 1; S-(hydroxyalkyl)glutathione lyase A1; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase 2; glutathione S-transferase Ha subunit 1; testicular tissue protein Li 80
• Gene ID: 2938
• mRNA Refseq: NM_145740.4
• Protein Refseq: NP_665683.1
• UniProt ID: P08263