Recombinant Human GRP Protein, His-tagged

• Cat.No.: GRP-1199H
• Product Overview: Recombinant Human GRP Protein (Ser54-Gln148) with His tag was expressed in 293F.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Ser54-Gln148
• Description: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 11.9 kDa; Accurate Molecular Mass: 16 kDa
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: GRP gastrin releasing peptide [ Homo sapiens (human) ]
• Official Symbol: GRP
• Synonyms: GRP; gastrin releasing peptide; BN; GRP-10; proGRP; preproGRP; gastrin-releasing peptide; bombesin; neuromedin C; pre-progastrin releasing peptide; prepro-GRP; testicular tissue protein Li 103
• Gene ID: 2922
• mRNA Refseq: NM_002091
• Protein Refseq: NP_002082
• MIM: 137260
• UniProt ID: P07492