Recombinant Human GRK5
Cat.No. : | GRK5-26369TH |
Product Overview : | Recombinant full length GRK5 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal enzyme tag, MW 95 kDa. |
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Species : | Human |
Tag : | Non |
Description : | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). |
Tissue specificity : | Highest levels in heart, placenta, lung >skeletal muscle >brain, liver, pancreas >kidney. |
Biological activity : | Specific Activity: >33 nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.Contains 1 RGS domain. |
Full Length : | Full L. |
Gene Name | GRK5 G protein-coupled receptor kinase 5 [ Homo sapiens ] |
Official Symbol | GRK5 |
Synonyms | GRK5; G protein-coupled receptor kinase 5; GPRK5; |
Gene ID | 2869 |
mRNA Refseq | NM_005308 |
Protein Refseq | NP_005299 |
MIM | 600870 |
Uniprot ID | P34947 |
Chromosome Location | 10q24-qter |
Pathway | Alpha-synuclein signaling, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Endocytosis, organism-specific biosystem; |
Function | ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; phospholipid binding; protein binding; |
◆ Recombinant Proteins | ||
Grk5-1051M | Recombinant Mouse Grk5 Protein, MYC/DDK-tagged | +Inquiry |
GRK5-75HFL | Active Recombinant Full Length Human GRK5 Protein, N-His-tagged | +Inquiry |
GRK5-5356H | Recombinant Human GRK5 Protein, GST-tagged | +Inquiry |
GRK5-1735H | Recombinant Human GRK5 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
GRK5-2366R | Recombinant Rat GRK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
GRK5-640HCL | Recombinant Human GRK5 cell lysate | +Inquiry |
Not For Human Consumption!
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