Recombinant Human GRK4 Protein (Ala187-Phe449), His tagged
Cat.No. : | GRK4-2601H |
Product Overview : | Recombinant human GRK4 (Ala187-Phe449) protein fused with His tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | Ala187-Phe449 |
Description : | Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. |
Molecular Mass : | 30.65 kDa |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name | GRK4 G protein-coupled receptor kinase 4 [ Homo sapiens (human) ] |
Official Symbol | GRK4 |
Synonyms | GRK4; G protein-coupled receptor kinase 4; G protein coupled receptor kinase 2 like (Drosophila), GPRK2L; GPRK4; ITI1; IT11; GRK4a; GPRK2L; |
Gene ID | 2868 |
mRNA Refseq | NM_001004056 |
Protein Refseq | NP_001004056 |
MIM | 137026 |
UniProt ID | P32298 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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