Recombinant Human GPBP1 Protein, GST-tagged

• Cat.No.: GPBP1-5143H
• Product Overview: Human GPBP1 full-length ORF (AAH00267.1, 1 a.a. - 181 a.a.) recombinant protein with GST tag at N-terminal.

Specification

• Description: This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 47.2 kDa
• AA Sequence: MRTDKKSEFLKALKRDRVEEEHEDESRAGSEKDDDSFNLHNSNSTHQERDINRNFDENEIPQENGNASVISQQIIRSSTFPQTDVLSSSLEAEHRLLKEMGWQEDSENDETCAPLTEDEMREFQVISEQLQKNGLRKNGILKNGLICDFKFGPWKNSTFKPTTENDDTETSSSDTSDDDDV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GPBP1 GC-rich promoter binding protein 1 [ Homo sapiens ]
• Official Symbol: GPBP1
• Synonyms: GPBP1; GC-rich promoter binding protein 1; vasculin; DKFZp761C169; vascular wall-linked protein; GPBP; SSH6; VASCULIN; MGC126339
• Gene ID: 65056
• mRNA Refseq: NM_001127235
• Protein Refseq: NP_001120707
• MIM: 608412
• UniProt ID: Q86WP2