Recombinant Human GNPNAT1, His-tagged

• Cat.No.: GNPNAT1-933H
• Product Overview: Recombinant human GNPNAT1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.1 kDa (207aa).

Specification

• Cat. No.: GNPNAT1-933H
• Description: Glucosamine-phosphate N-acetyltransferase, also known GNPNAT1, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. It is localized to the Golgi apparatus and the endosome. It is important for UDPGlcNAc biosynthesis pathway. GNPNAT1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
• Source: E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSMKPDETP MFDPSLLKEV DWSQNTATFS PAISP THPGE GLVLRPLCTA DLNRGFFKVL GQLTETGVVSPEQFMKSFEH MKKS GDYYVT VVEDVTLGQI VATATLIIEH KFIHSCAKRG RVEDVVVSDE CRGKQLGKLL LSTLTLLSKK LNCYKITLECLPQNVGFYKK FGYTVSEENY MCRRFLK.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Amino sugar and nucleotide sugar metabolism; Metabolism of proteins

Gene Information

• Gene Name: GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 [ Homo sapiens ]
• Synonyms: glucosamine-phosphate N-acetyltransferase 1; GNPNAT; Gpnat1; FLJ10607; GNPNAT1; glucosamine 6-phosphate N-acetyltransferase; phosphoglucosamine acetylase; phosphoglucosamine transacetylase; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; EC 2.3.1.4; GNA1
• Gene ID: 64841
• mRNA Refseq: NM_198066
• Protein Refseq: NP_932332
• UniProt ID: Q96EK6
• Chromosome Location: 14q22.1
• Function: acyltransferase activity; monosaccharide binding; transferase activity; glucosamine 6-phosphate N-acetyltransferase activity