Recombinant Human GJB3 Protein, GST-tagged

• Cat.No.: GJB3-4930H
• Product Overview: Human GJB3 full-length ORF ( AAH12918.1, 1 a.a. - 270 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
• Molecular Mass: 55.44 kDa
• AA Sequence: MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GJB3 gap junction protein, beta 3, 31kDa [ Homo sapiens ]
• Official Symbol: GJB3
• Synonyms: GJB3; gap junction protein, beta 3, 31kDa; DFNA2, EKV, erythrokeratodermia variabilis, gap junction protein, beta 3, 31kD (connexin 31), gap junction protein, beta 3, 31kDa (connexin 31); gap junction beta-3 protein; connexin 31; CX31; connexin-31; EKV; DFNA2; DFNA2B; FLJ22486; MGC102938
• Gene ID: 2707
• mRNA Refseq: NM_001005752
• Protein Refseq: NP_001005752
• MIM: 603324
• UniProt ID: O75712