Recombinant Human GIP, GST-tagged

• Cat.No.: GIP-13264H
• Product Overview: Recombinant Human GIP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 22-153a.a.
• Description: This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternate splicing results in two readthrough transcript variants that encode different isoforms. One of the readthrough variants encodes a fusion protein that shares sequence identity with each individual gene product. The other variant encodes a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to frameshifts relative to the downstream gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GIP gastric inhibitory polypeptide [ Homo sapiens ]
• Official Symbol: GIP
• Synonyms: GIP; gastric inhibitory polypeptide; glucose dependent insulinotropic polypeptide; glucose-dependent insulinotropic polypeptide
• Gene ID: 2695
• mRNA Refseq: NM_004123
• Protein Refseq: NP_004114
• MIM: 137240
• UniProt ID: P09681
• Chromosome Location: 17q21.3-q22
• Pathway: Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem
• Function: hormone activity