Recombinant Human GDAP1L1 Protein, MYC/DDK-tagged

• Cat.No.: GDAP1L1-648H
• Product Overview: Recombinant Human GDAP1L1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 [ Homo sapiens ]
• Official Symbol: GDAP1L1
• Synonyms: ganglioside induced differentiation associated protein 1-like 1; 4213; Ensembl:ENSG00000124194; DKFZp761K228; ganglioside-induced differentiation-associated protein 1-like 1;GDAP1-L1; dJ881L22.1; dJ995J12.1.1
• Gene ID: 78997
• mRNA Refseq: NM_024034
• Protein Refseq: NP_076939
• UniProt ID: B7Z621